On Biochemical Evolution: Lysine Formation in Higher Plants.

* This study was aided by a grant from the National Science Foundation. t Predoctoral Fellow of the National Cancer Institute, United States Public Health Service. t Predoctoral Fellow of the National Heart Institute, United States Public Health Service. § Summer Research Fellow of the United States Public Health Service, 1957; Summer Research Fellow of the National Science Foundation, 1958. 1 Harbury, H. A., and K. A. Foley, these PROCEEDINGS, 44, 662 (1958). 2 Maly, R., and R. Andreasch, Monatsh., 3, 108 (1882). 3 Kuhn, R., and K. Reinemund, Ber. Deut. chem. Ges., 67, 1934 (1934). 4 Harbury, H. A., J. Biol. Chem., 225, 1009 (1957). 5 We are grateful to Dr. E. C. Weinbach for the gift of a highly purified sample. 6 The following abbreviations are used: FMN, flavin mononucleotide; FMNH2, reduced flavin mononucleotide; FAD, flavin adenine dinucleotide; AMP, adenosine-5'-phosphate; iEtm, the difference in potential between half-reduced oxidation-reduction systems. 7 Weber, G., Biochem. J., 47, 114 (1950). 8 Lowe, H. J., and W. M. Clark, J. Biol. Chem., 221, 983 (1956). 9 Mulliken, R. S., J. Am. Chem. Soc., 74, 811 (1952). 10 Mulliken, R. S., J. Phys. Chem., 56, 801 (1952). 11 Isenberg, I., and A. Szent-Gyorgyi, these PROCEEDINGS, 44, 857 (1958). 12 Pullman, B., and A. Pullman, these PROCEEDINGS, 44, 1197 (1958). 13 Ibid., 45, 136 (1959). 14 Fujimori, E., these PROCEEDINGS, 45, 133 (1959). 11 Cilento, G., and P. Giusti, J. Am. Chem. Soc., 81, 3801 (1959). 16 Brooker, L. G. S., G. H. Keyes, and 1). W. Heseltine, J. Am. Chem. Soc., 73, 5350 (1951).